El Instituto de Investigación Sanitaria Aragón en colaboración con Patricia Sancho, Grupo Metabolismo y Células Madre Tumorales y Facultad de Medicina, Universidad de Zaragoza, organizan el Miércoles 24 de noviembre de 2023 a las 13:00 el Seminario Biomédico «Identifying novel vulnerabilities in breast cancer brain metastasis»

Summary:

Breast cancer brain metastasis (BCBM) is an aggressive form of metastatic spread occurring in 10-30% of breast cancer patients, with rising incidence. Partially due to the lack of representative experimental BCBM models, unique biological and molecular features of BCBMs are not yet exploited sufficiently in the development of therapeutic approaches specific to this condition. In the present study utilizing clinical datasets, mouse and patient-derived brain metastatic models we explored the role of the tyrosine kinase receptor, RET, in promoting breast cancer brain metastasis.

Speaker:

Dr Petra Jagušt, PhD