Sobre el grupo


Investigador Principal

Ángel Luis García Otín 

Equipo

Ana Marcén Miravete, Ana Portolés Ocampo, Ángela Juez Jiménez, Antonio Asso Abadía, Clara Bergua Martínez, Eva Mª Moreno Esteban, Eva María Santamaría Luna, Gabriel Galache Osuna, Javier Jimeno Sánchez, José Antonio Diarte de Miguel, José Enrique Castillo Lueña, José Javier Salazar González, José Ramón Laperal Mur, Juan Carlos Porres Aspiroz, Juan Sánchez-Rubio Lezcano, Laura Álvarez Roy, Mª Carmen Aured Guallar, Mª Cristina De Torres Olson, Mª Cruz Ferrer Gracia, Mª Rosario Ortas Nadal, María Teresa Blasco Peiró, Maruan Carlos Chabbar Boudet, Pilar Lapuente González, Silvia Gómez Ardanaz, Teresa Oloriz Sanjuán

Instituto Aragonés de Ciencias de la Salud

Líneas de Investigación


Aplicación de progenitores endoteliales en ingeniería de tejidos

Biología básica de células progenitoras vasculares

Uso de células endoteliales progenitoras circulantes (CEPCs) como biomarcadores de enfermedad cardiovascular

Uso de progenitores endoteliales en terapia celular

Publicaciones más relevantes


Guedeney P, Chieffo A, Snyder C, Mehilli J, Petronio A, Claessen B, Sartori S, Lefevre T, Presbitero P, Capranzano P, Tchetche D, Iadanza A, Sardella G, Van Mieghem N, Chandrasekhar J, Vogel B, Sorrentino S, Kalkman D, Meliga E, Dumonteil N, Fraccaro C, Trabattoni D, Mikhail G, Ferrer M, Naber C, Kievit P, Baber U, Sharma S, Morice M, Mehran R, WIN-TAVI Investigators. Impact of Baseline Atrial Fibrillation on Outcomes Among Women Who Underwent Contemporary Transcatheter Aortic Valve Implantation (from the Win-TAVI Registry). Am J Cardiol. 2018. 122(11): 1909 - 1916. 10.1016/j.amjcard.2018.08.036.

Perez-Laguna V, Garcia-Malinis A, Aspiroz C, Rezusta A, Gilaberte Y. A ntimicrobial effects of photodynamic therapy. G Ital Dermatol Venereol. 2018. 153(6): 833 - 846. 10.23736/S0392-0488.18.06007-8.

Di Marco A, Oloriz Sanjuan T, Paglino G, Baratto F, Vergara P, Bisceglia C, Trevisi N, Sala S, Marzi A, Gulletta S, Cireddu M, Anguera I, Della Bella P. Late potentials abolition reduces ventricular tachycardia recurrence after ablation especially in higher-risk patients with a chronic total occlusion in an infarct-related artery. J. Cardiovasc. Electrophysiol.. 2018. 29(8): 1119 - 1124. 10.1111/jce.13488.

Comin-Colet J, Manito N, Segovia-Cubero J, Delgado J, Pinilla J, Almenar L, Crespo-Leiro M, Sionis A, Blasco T, Pascual-Figal D, Gonzalez-Vilchez F, Lambert-Rodriguez J, Grau M, Bruguera J, LION-HEART Study Investigators. Efficacy and safety of intermittent intravenous outpatient administration of levosimendan in patients with advanced heart failure: the LION-HEART multicentre randomised trial. Eur. J. Heart Fail.. 2018. 20(7): 1128 - 1136. 10.1002/ejhf.1145.

Rodriguez-Manero M, Oloriz T, de Waroux J, Burri H, Kreidieh B, de Asmundis C, Arias M, Arbelo E, Fernandez B, Fernandez-Armenta J, Basterra N, Izquierdo M, Diaz-Infante E, Ballesteros G, Lopez A, Garcia-Bolao I, Benezet-Mazuecos J, Exposito-Garcia V, Larraitz-Gaztanaga, Martinez-Sande J, Garcia-Seara J, Gonzalez-Juanatey J, Peinado R. Long-term prognosis of patients with life-threatening ventricular arrhythmias induced by coronary artery spasm. Europace. 2018. 20(5): 851 - 858. 10.1093/europace/eux052.

de Frutos L, Cebolla J, Irun P, Kohler R, Giraldo P. The erythrocyte osmotic resistance test as screening tool for cholesterol-related lysosomal storage diseases. Clin Chim Acta. 2018. 480: 161 - 165. 10.1016/j.cca.2018.02.010.

Lozano-Gerona J, Garcia-Otin A. ImageJ-based semiautomatic method to analyze senescence in cell culture. Anal. Biochem.. 2018. 543: 30 - 32. 10.1016/j.ab.2017.11.020.

Puri R, Otaegui I, Sabate M, Serra-Penaranda A, Puigfel M, de Prado A, Nombela-Franco L, Hernandez J, Nadal R, Iniguez-Romo A, Jimenez G, Fernandez-Vazquez F, Cuellas-Ramon C, Gonzalo N, Diaz V, Duocastella L, Molina M, Amoros M, Perez I, Perez A, Beaumont E, Nicholls S, del Blanco B, Rodes-Cabau J. Three- and 6-month optical coherence tomographic surveillance following percutaneous coronary intervention with the Angiolite (R) drug-eluting stent: The ANCHOR study. Catheter. Cardiovasc. Interv.. 2018. 91(3): 435 - 443. 10.1002/ccd.27189.

Mebazaa A, Motiejunaite J, Gayat E, Crespo-Leiro M, Lund L, Maggioni A, Chioncel O, Akiyama E, Harjola V, Seferovic P, Laroche C, Julve M, Roig E, Ruschitzka F, Filippatos G, ESC Heart Failure Long-Term Regist. Long-term safety of intravenous cardiovascular agents in acute heart failure: results from the European Society of Cardiology Heart Failure Long-Term Registry. Eur. J. Heart Fail.. 2018. 20(2): 332 - 341. 10.1002/ejhf.991.

de Frutos L, Cebolla J, Irun P, Kohler R, Giraldo P. Erythrocyte osmotic resistance test as a screening tool for lysosomal diseases. Mol. Genet. Metab.. 2018. 123(2): 89 - 89. 10.1016/j.ymgme.2017.12.229.

Chieffo A, Petronio A, Mehilli J, Chandrasekhar J, Sartori S, Lefevre T, Presbitero P, Capranzano P, Tchetche D, Iadanza A, Sardella G, Van Mieghem N, Meliga E, Dumonteil N, Fraccaro C, Trabattoni D, Mikhail G, Sharma S, Ferrer M, Naber C, Kievit P, Baber U, Snyder C, Sharma M, Morice M, Mehran R, WIN-TAVI Investigators. 1-Year Clinical Outcomes in Women After Transcatheter Aortic Valve Replacement Results From the First WIN-TAVI Registry. JACC-Cardiovasc. Interv.. 2018. 11(1): 1 - 12. 10.1016/j.jcin.2017.09.034.

Olivan-Viguera A, Garcia-Otin A, Lozano-Gerona J, Abarca-Lachen E, Garcia-Malinis A, Hamilton K, Gilaberte Y, Pueyo E, Kohler R. Pharmacological activation of TRPV4 produces immediate cell damage and induction of apoptosis in human melanoma cells and HaCaT keratinocytes. PLoS One. 2018. 13(1): e0190307. 10.1371/journal.pone.0190307.

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