GIIS112 – Cancer and Radiation Biology

Albert Herms*, David Fernandez-Antoran*, Maria P. Alcolea*, Argyro Kalogeropoulou, Ujjwal Banerjee, Gabriel Piedrafita, Emilie Abby, Jose Antonio Valverde-Lopez, Inês S.
Ferreira, Stefan C. Dentro, Swee Hoe Ong, Bartomeu Colom, Kasumi Murai, Charlotte King, Krishnaa Mahbubani, Kourosh Saeb-Parsy, Alan R Lowe, Moritz Gerstung, Philip H
Jones. Self-sustaining long-term 3D epithelioid cultures reveal drivers of clonal expansion in esophageal epithelium. Nature Genetics, 2024.
https://doi.org/10.1038/s41588-024-01875-8 *co-first authors. (1er decil).

Albert Herms*, Bartomeu Colom*, Gabriel Piedrafita, Emilie Abby, Kasumi Murai, Charlotte King, Swee Hoe Ong, David Fernandez-Antoran, Michael W J Hall, Christopher Bryant, Roshan K Sood, Joanna C Fowler, Christian Frezza, Bart Vanhaesebroeck, Philip H Jones.Organismal metabolism regulates the expansion of oncogenic PIK3CA mutant clones in normal esophagus. Nature Genetics, 2024.
https://doi.org/10.1038/s41588-024-01891-8 * co-first authors. (1er decil)

Regina Hoo*, Elias R. Ruiz-Morales*, Iva Kelava, Mukul Rawat, Cecilia Icoresi Mazzeo, Elizabeth Tuck, Carmen Sancho-Serra, Sara Chelaghma, Alexander V. Predeus, Simon Murray, David Fernandez-Antoran, Ross F. Waller, Damiana Álvarez-Errico, Marcus C.S. Lee, Roser Vento-Tormo. Early infection response of the first trimester human placenta at single-cell scale. Cell Systems, 2024
https://doi.org/10.1016/j.cels.2024.04.002 * co-first authors. (1er decil)

Kasumi Murai, Stefan Dentro, Swee Hoe Ong, Roshan Sood, David FernandezAntoran, Albert Herms, Vasiliki Kostiou, Benjamin A Hall, Moritz Gerstung, Philip H Jones. p53 mutation in normal esophagus promotes multiple stages of carcinogenesis but is constrained by clonal competition. Nat Commun 13, 6206 (2022).
https://doi.org/10.1038/s41467-022-33945-y. (1er decil)

B. Colom, A. Herms, M. W. J. Hall, S. C. Dentro, C. King, R. K. Sood, M. P. Alcolea, G. Piedrafita, D. Fernandez-Antoran, S. H. Ong, J. C. Fowler, K. T. Mahbubani, K. SaebParsy, M. Gerstung, B. A. Hall & P. H. Jones. Mutant clones in normal epithelium outcompete and eliminate emerging tumours. Nature
https://doi.org/10.1038/s41586-021-03965-7. (1er decil)

Joanna Fowler, Charlotte King, Christopher Bryant, Michael Hall, Roshan Sood, Swee Hoe Ong, Eleanor Earp, David Fernandez-Antoran, Jonas Koeppel, Stefan Dentro, David Shorthouse, Amer Durrani, Kate Fife, Edward Rytina, Doreen Milne, Amit Roshan, Krishnaa Mahububani, Kourosh Saeb-Parsy, Benjamin Hall, and Moritz Gerstung, Philip H Jones. Selection of oncogenic mutant clones in normal human skin varies with body site. Cancer Discovery, October 21 (2020).
https://doi.org/10.1158/2159-8290.CD-20-1092. (1er decil)

Gabriel Piedrafita, Vasiliki Kostiou, Agnieszka Wabik, Bartomeu Colom, David Fernandez Antoran, Albert Herms, Kasumi Murai, Benjamin A Hall, Philip H Jones. A singleprogenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice. Nat Commun 11, 1429 (2020).
https://doi.org/10.1038/s41467-020-15258-0. (1er decil)

David Fernandez-Antoran, Gabriel Piedrafita, Kasumi Murai, Swee How, Albert Herms, Christian Frezza and Philip H. Jones. Outcompeting p53-mutant cells in the normal esophagus by redox manipulation. Cell Stem Cell, 2019.
https://doi.org/10.1016/j.stem.2019.06.011 (1er decil)

Cristina Uruén, Jorge Gimeno , Marina Sanz, Lorenzo Fraile, Clara M. Marín, Jesús Arenas. Invasive Streptococcus suis isolated in Spain contain a highly promiscuous and dynamic resistome. Frontiers in Cellular and Infection Microbiology Vol.13, 2024.
https://doi.org/10.3389/fcimb.2023.1329632 (1 er cuartil)

Pilar Espiau-Romera, Andrés Gordo-Ortiz, Inés Ortiz-de-Solórzano, Patricia Sancho. Metabolic features of tumor-derived extracellular vesicles: challenges and opportunities. Extracellular Vesicles and Circulating Nucleic Acids, 2024.
https://doi.org/10.20517/evcna.2024.12 (3er cuartil)